Little-Known Causes of Miscarriage

Miscarriage is such a taboo subject; nobody wants to talk about it, but it is a topic that should be discussed. Women should know they are not alone. According to Mayo Clinic, 10 to 20 percent of all known pregnancies result in miscarriage; however, the actual number is likely higher as most miscarriages end so early during pregnancy and a woman may not even realize she’s pregnant. Miscarriage can occur due to several factors.



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Thyroid Disorder

Whether suffering from hypothyroidism or hyperthyroidism, thyroid disorders are a huge culprit with infertility and miscarriages. According to Malpani Infertility Clinic, when a woman’s thyroid function is low, her body tries to compensate and to do so, it produces hormones that can suppress ovulation; similarly, a thyroid that produces too much hormone can interfere with estrogen, leading to abnormal uterine bleeding or making the uterus unfavorable for implantation.


According to Dr. Nowacki, uncontrolled diabetes can lead to a miscarriage. Patients struggling with diabetes should consult their healthcare provider prior to trying to conceive to ensure their blood sugar is at proper levels.

Immunologic Disorders

This one is still controversial among many doctors; however, it’s a debate that is ongoing and is still being researched. According to the American College of Obstetricians and Gynecologists, they agree that specific autoimmune disorders do play a critical role in miscarriage, as well as recurrent miscarriages.

Blood Clotting Disorders

Blood clotting disorders, such as Factor V Leiden are typically rare, but they do occur, and they can cause miscarriages. Even though this is a cause for miscarriage, it’s not a common one, compared to other causes.

Cervical Insufficiency

An incompetent cervix means a weak cervix; it won’t be able to hold a pregnancy. A miscarriage resulting from an incompetent cervix will usually occur in the second trimester. Few symptoms appear before a miscarriage caused by cervical insufficiency; a woman may notice fetal tissue being expelled without hardly any pain or experience sudden pressure.


Research has revealed there is a higher risk for miscarriage if one or more certain infections are present. The infections include parvovirus, HIV, gonorrhea, cytomegalovirus, measles, rubella, mumps, and listeria.

Environmental Toxins

Certain environmental factors can contribute to the cause of miscarriage. The toxins include anesthetic gasses, large doses of radiation, ethylene oxide, benzene, formaldehyde, arsenic, and lead.

Sperm DNA Fragmentation

Another cause for miscarriage that is typically overlooked, but also very common, is sperm DNA fragmentation. This condition occurs when strands of sperm DNA are actually broken and can’t deliver DNA to the egg. With different levels of severity, miscarriage is 2 to 5 times more for men who have the condition, in comparison to men who have healthy sperm.

Antiphospholipid Syndrome

Thrombophilias, a group of disorders that enhance the chances of clotting. When this condition has been inherited, it has not been shown to lead to miscarriage; however, those that are acquired can. The most common type, the antiphospholipid syndrome can cause elevation within the antiphospholipid antibodies which can lead to blood clotting, resulting in interference with implantation and embryo growth and development.


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