Are you the kind of person that takes action in just about every part of your life, but come up short when it comes to your own health? For the millions of women suffering from chronic idiopathic constipation (CIC), the condition and some of the available treatments can significantly disrupt their daily lives.1,2

People who, in every other aspect of their life, are doers with a plan of action and who accomplish great things can become overwhelmed by their condition and feel defeated. My dear friend is just this type of woman. She has three kids, had been active at her church and in the community, and had run a tight ship at home, but I’ve witnessed how she retreated from the world. I had no idea what she might be going through until I recently mentioned I was working with a company to raise awareness about CIC. With a look of profound disbelief on her face, she told me she had been contending with CIC for years.

Working motherWhen I met Karen* in college, she was the ultimate doer. We called her ‘The Cruise Director.’ She was always organizing everyone for outings and was on top of it all whenever we got where we were going. She moved close to me years later and so much had changed. Sure, she was busy with her kids, but other things had changed about the way she went about her life. When we talked on the phone, she was just as on top of everything like before, but instead of being out and about, it seemed like she was avoiding certain situations. Karen was one of the 1 in 7 adults in the U.S. suffering from CIC. 2 CIC is a functional gastrointestinal (GI) disorder that is typically characterized by infrequent bowel movements (fewer than three a week) where there is no identifiable cause.1,2 Symptoms of CIC can vary but may include difficult-to-pass stools, straining and discomfort.1 But at times Karen lived a bowel-centered life, suffering just as much from the lifestyle adjustments she made and treatments she took to deal with her CIC. At times, Karen added copious amounts of fiber and water to her diet along with OTC laxatives. But she often was left feeling like she was swinging between the discomfort of chronic constipation and the issues with diarrhea and nausea from the methods she was using on her own. She felt like her whole life revolved around the bathroom.

Fortunately, there are other options for those contending with CIC. Click here to learn more about Trulance™ (plecanatide), an available treatment option indicated for adults with CIC.3

Are you a woman who takes the bull by the horns with nearly every aspect of your life? Is it time to talk to your doctor? When managing constipation, you shouldn’t have to make compromises. If like my friend Karen, you feel like your life seems to revolve around when and where you go to the bathroom, now may be the time to talk to your doctor about Trulance. Trulance is indicated for adults with CIC.3 Diarrhea is the most common side effect and can sometimes be severe.3 It is important to discuss the potential benefits and side effects with your doctor.3 See additional important safety information below.

When you head in to visit your doctor it might be helpful to bring along the following information so that they have a complete picture of what is going on. Karen has made many trips to talk to doctors about her CIC. She noted that being as prepared as possible made for a more productive trip.

Karen suggests prepping for doctor’s visits by doing the following:

  • Track what you’ve been eating. Maybe even keep a daily log of what you eat and the time of day that you eat it.
  • Track and record any medications and supplements you’ve been using. Don’t forget to include OTC medications.
  • Track your exercise habits. Include the type of activity and the time of day.
  • Make note of what you have tried to do to treat your CIC and how it affected you.

[1] Thomas R, Luthin D. Current and emerging treatments for irritable bowel syndrome with constipation and chronic idiopathic constipation: focus on prosecretory agents. Pharmacotherapy Pub. 2015; 613-630.

[2] Suares NC, Ford AC. Prevalence of, and risk factors for chronic idiopathic constipation in the community: systematic review and meta-analysis. Am J Gastroenterol. 2011;106(9):1582-1591.

[3] Trulance™ [Prescribing Information]. Synergy Pharmaceuticals, Inc., New York City, New York: January 2017. Accessed July 25, 2017.

What is Trulance?

Trulance™ (plecanatide) 3 mg tablets is a prescription medicine used in adults to treat a type of constipation called chronic idiopathic constipation (CIC). “Idiopathic” means the cause of the constipation is unknown. It is not known if Trulance is safe and effective in children less than 18 years of age.


  • Do not give Trulance to children who are less than 6 years of age. It may harm them.
  • You should not give Trulance to children 6 years to less than 18 years of age. It may harm them.
  • Do not take Trulance if a doctor has told you that you have a bowel blockage (intestinal obstruction).

Before you take Trulance, tell your doctor:

  • If you have any other medical conditions.
  • If you are pregnant or plan to become pregnant. It is not known if Trulance will harm your unborn baby.
  • If you are breastfeeding or plan to breastfeed. It is not known if Trulance passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take Trulance.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Side Effects

Diarrhea is the most common side effect and can sometimes be severe. Diarrhea often begins within the first 4 weeks of Trulance treatment. Stop taking Trulance and call your doctor right away if you get severe diarrhea.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Trulance. For more information, ask your doctor or pharmacist.

You are encouraged to report side effects to the FDA. Visit or call 1-800-FDA-1088 or you can report side effects to Synergy Pharmaceuticals at 1-888-869-8869.

Please also see Medication Guide within the full Prescribing Information.

*Name and identifying details changed to protect patient privacy.

Comments submitted may be displayed on other websites owned by the sponsoring brand.

This is a sponsored conversation written by me on behalf of Synergy Pharmaceuticals. The opinions and text are all mine.